Mood swings

Mood Swings in Menopause: Why They Happen

September 02, 20251 min read

Emotional ups and downs are common during perimenopause and menopause. Many women feel irritable, tearful, or easily frustrated, often without clear triggers.

The Hormone Connection
Estrogen influences neurotransmitters like serotonin (which stabilizes mood) and dopamine (linked to motivation and pleasure). Progesterone produces calming compounds that act on the brain. As these hormones fluctuate or decline, mood regulation becomes more challenging, leading to swings in emotions.

Other Contributing Factors
Sleep disruption, hot flashes, and increased stress during midlife can further amplify mood instability. Fatigue and hormonal changes often combine to create a cycle of emotional sensitivity.

Mood swings

What Helps

  • Meals: Balanced protein + complex carbs prevent dips

  • Movement: Exercise releases endorphins

  • Mind: Mindfulness + therapy regulate emotions

  • Meds: Hormone therapy or SSRIs if needed

The Bottom Line
Mood swings during menopause are not a sign of weakness. They are a biological response to hormonal changes and can be managed with the right strategies.


Physician Founder of Midlife reMDy

Caissa Troutman MD

Physician Founder of Midlife reMDy

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